Okamura T, Watanabe H, Ueda K, Otaguro K, Nakamura T
Hinyokika Kiyo. 1983 Jan;29(1):67-72.
Carcinoma of the bladder diverticulum is a relatively rare disease. However, its preoperative diagnosis is often difficult. Also, infiltration occurs easily because the diverticulum wall is thin, and prognosis is said to be relatively poor. Histologically, the occurrence rate of squamous cell carcinoma is markedly high. We have experienced a case of squamous cell carcinoma in the bladder diverticulum occurring simultaneously with transitional cell carcinoma of the bladder; and, report this case along with a review of the literature. The patient, a 79-year-old male, had sudden macroscopic hematuria on December 15, 1980, and went to the urology department of a separate hospital. IVU showed distortion of the right ureter, and the patient was referred to our hospital. Cystoscopy revealed a diverticulum in the right wall of the bladder. In the posterior wall of the bladder 2 papillary sessile tumors were also detected. Pathological diagnosis by cold punch biopsy done after the patient was admitted to hospital revealed a grade III transitional cell carcinoma. Total cystectomy + bilateral cutaneous ureterostomy was performed. The diverticulum was in the right wall of the bladder and a papillary sessile tumor with a diameter of 4 cm was found in the diverticulum. A papillary sessile tumor 2 cm in diameter was found in the left bladder wall. Histopathological diagnosis of the tumor in the diverticulum was squamous cell carcinoma ( pG2 , pT3b , ly1, v(-) INF beta) and that of the tumor in the bladder was transitional cell carcinoma ( ( pG3 , pT2 , ly1, v(-), INF gamma).(ABSTRACT TRUNCATED AT 250 WORDS)
膀胱憩室癌是一种相对罕见的疾病。然而，其术前诊断往往困难。此外，由于憩室壁薄，容易发生浸润，据说预后相对较差。组织学上，鳞状细胞癌的发生率明显较高。我们遇到过一例膀胱憩室鳞状细胞癌与膀胱移行细胞癌同时发生的病例；并报告此病例并复习文献。患者为79岁男性，1980年12月15日突然出现肉眼血尿，前往另一家医院的泌尿外科就诊。静脉肾盂造影显示右输尿管扭曲，患者被转诊至我院。膀胱镜检查发现膀胱右壁有一个憩室。在膀胱后壁还发现了2个乳头状无蒂肿瘤。患者入院后经冷切活检的病理诊断为III级移行细胞癌。行全膀胱切除术+双侧皮肤输尿管造口术。憩室位于膀胱右壁，在憩室内发现一个直径4cm的乳头状无蒂肿瘤。在膀胱左壁发现一个直径2cm的乳头状无蒂肿瘤。憩室内肿瘤的组织病理学诊断为鳞状细胞癌（pG2，pT3b，ly1，v(-)，INFβ），膀胱内肿瘤的组织病理学诊断为移行细胞癌（pG3，pT2，ly1，v(-)，INFγ）。（摘要截短至250字）
