Savoia D, Gribaudo G M, Angeretti A, Negro Ponzi A
Boll Ist Sieroter Milan. 1983;62(6):489-494.
Forty recently isolated hospital strains of Pseudomonas aeruginosa were assayed to determine the part played by the production of beta-lactamase in their resistance to beta-lactamic antibiotics, together with the relative importance of constitutive and inducible enzymes in such resistance in the case of carbenicillin (CB). 62.5% were CB-resistant. In 56% of cases, this resistance was due to the production of a class Vd constitutive enzyme, whereas it was ascribable to intrinsic resistance in the other 44%.
对40株最近从医院分离出的铜绿假单胞菌菌株进行了分析，以确定β-内酰胺酶的产生在其对β-内酰胺类抗生素耐药性中所起的作用，以及在羧苄西林（CB）耐药情况下组成型酶和诱导型酶在这种耐药性中的相对重要性。62.5%的菌株对CB耐药。在56%的病例中，这种耐药性是由于产生了Vd类组成型酶，而在其他44%的病例中则归因于固有耐药性。
