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来自囊性纤维化患者的铜绿假单胞菌菌株的噬菌体导致的黏液样转化

Mucoid conversion by phages of Pseudomonas aeruginosa strains from patients with cystic fibrosis.

作者信息

Miller R V, Rubero V J

出版信息

J Clin Microbiol. 1984 May;19(5):717-9. doi: 10.1128/jcm.19.5.717-719.1984.

Abstract

A total of 21 of 22 independent isolates of cystic fibrosis-associated Pseudomonas aeruginosa were found to be lysogenic for DNA-containing, complex capsid viruses. Several of the phages demonstrated the ability to select mucoid cells from populations of nonmucoid bacteria. Conversion to mucoid growth was more frequently achieved when phages were isolated from mucoid as opposed to nonmucoid cystic fibrosis-associated strains.

摘要

在22株与囊性纤维化相关的铜绿假单胞菌独立分离株中,共有21株被发现对含DNA的复杂衣壳病毒具有溶原性。几种噬菌体表现出从非黏液性细菌群体中选择黏液性细胞的能力。与从非黏液性囊性纤维化相关菌株中分离的噬菌体相比,当从黏液性菌株中分离噬菌体时,更频繁地实现向黏液性生长的转化。

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