范科尼贫血中的红细胞己糖激酶

Red blood cell hexokinase in Fanconi's anemia.

作者信息

Magnani M, Novelli G, Stocchi V, Alimena G, Dallapiccola B

出版信息

Acta Haematol. 1984;71(5):341-4. doi: 10.1159/000206612.

DOI:10.1159/000206612

Abstract

The activity of ten red blood cell enzymes, including hexokinase, has been measured in 6 Fanconi's anemia patients. In disagreement with previous reports, in no instance were reduced or increased hexokinase levels found. Furthermore, the hexokinase isozymic pattern, thermostability, pH dependence of activity and kinetic properties were also in the normal range.

摘要

已对6例范科尼贫血患者的10种红细胞酶（包括己糖激酶）的活性进行了测定。与之前的报告不同，未发现己糖激酶水平降低或升高的情况。此外，己糖激酶的同工酶模式、热稳定性、活性的pH依赖性和动力学特性也均在正常范围内。