Therapy of Waldenström's benign hypergammaglobulinaemia by regular plasmapheresis.

A patient with a 20-year history of Waldenström's hypergammaglobulinaemic purpura has over that time developed increasingly troublesome clinical symptoms of purpura and joint swelling, associated with a progressive increase in the level of polyclonal IgG. These symptoms have been controlled by the use of a regular plasmapheresis regime and associated with a reduction in IgG levels.