一名患有华氏巨球蛋白血症性紫癜患者体内IgA与温度依赖性IgG复合物的形成
IgA and temperature dependent IgG complex formation in a patient with Waldenström's hypergammaglobulinaemic purpura.
作者信息
Roberts-Thomson P J, Kemp A S
出版信息
Clin Exp Immunol. 1980 Jan;39(1):164-9.
Abstract
We describe a patient with hypergammaglobulinaemic purpura and show that the serum contains IgG and IgA immune complexes sedimenting between IgM and IgG on ultracentrifugation. The complexes containing IgG were markedly temperature dependent. A drop in temperature from 37 degrees C to 28 degrees C gave a seventeen-fold increase in the quantity of these complexes. This temperature dependency may be an important factor in localizing the major pathological manifestation of this disease to the skin.
摘要
我们描述了一位患有高球蛋白血症性紫癜的患者，并表明其血清中含有IgG和IgA免疫复合物，在超速离心时这些复合物沉降于IgM和IgG之间。含有IgG的复合物明显依赖温度。温度从37℃降至28℃会使这些复合物的量增加17倍。这种温度依赖性可能是将该疾病的主要病理表现定位于皮肤的一个重要因素。
相似文献
1
IgA and temperature dependent IgG complex formation in a patient with Waldenström's hypergammaglobulinaemic purpura.一名患有华氏巨球蛋白血症性紫癜患者体内IgA与温度依赖性IgG复合物的形成
Clin Exp Immunol. 1980 Jan;39(1):164-9.
2
3
Waldenström's hyperglobulinemic purpura: an unusual immune complex disorder.瓦尔登斯特伦高球蛋白血症性紫癜：一种罕见的免疫复合物疾病。
Clin Rheumatol. 1984 Jun;3(2):263-6. doi: 10.1007/BF02030769.
4
Monoclonal hyperglobulinemic purpura in multiple myeloma. IgG anti-IgG complexes as a pathogenetic factor.多发性骨髓瘤中的单克隆高球蛋白血症性紫癜。IgG抗IgG复合物作为致病因素。
Jpn J Dermatol B. 1972 Jun;82(2):41-6.
5
6
Hypergammaglobulinemic purpura of Waldenström: characterization of circulating immune complexes.瓦尔登斯特伦高丙种球蛋白血症性紫癜：循环免疫复合物的特征
Acta Haematol. 1983;69(3):152-7. doi: 10.1159/000206881.
7
Therapy of Waldenström's benign hypergammaglobulinaemia by regular plasmapheresis.通过定期血浆置换治疗瓦尔登斯特伦氏良性高丙种球蛋白血症。
Acta Haematol. 1984;71(5):345-9. doi: 10.1159/000206613.
8
[Waldenström's hyperglobulinemic purpura. Apropos of a case].[华氏巨球蛋白血症性紫癜。附病例报告]
Ann Pediatr (Paris). 1990 Oct;37(8):511-2.
9
Isolation of monoclonal rheumatoid factors in hypergammaglobulinemic purpura.
Diagn Immunol. 1984;2(4):219-23.
10
Clearance mediated by splenic macrophage membrane receptors for immune complexes in cutaneous vasculitis.皮肤血管炎中脾脏巨噬细胞膜受体介导的免疫复合物清除作用。
J Invest Dermatol. 1982 Mar;78(3):194-9. doi: 10.1111/1523-1747.ep12506441.
引用本文的文献
1
IgA containing immune complexes in dogs bearing a spontaneous mammary adenocarcinoma.患有自发性乳腺腺癌的犬体内含免疫球蛋白A的免疫复合物。
Clin Exp Immunol. 1982 Aug;49(2):433-40.
2
Studies on circulating soluble immune complexes of the liver disease. 7. Immune complexes in the clinical course and their ultracentrifugal analysis.肝脏疾病循环可溶性免疫复合物的研究。7. 临床病程中的免疫复合物及其超速离心分析。
Gastroenterol Jpn. 1981;16(2):186-92. doi: 10.1007/BF02774393.
3
Waldenström's hyperglobulinemic purpura: an unusual immune complex disorder.瓦尔登斯特伦高球蛋白血症性紫癜：一种罕见的免疫复合物疾病。
Clin Rheumatol. 1984 Jun;3(2):263-6. doi: 10.1007/BF02030769.
本文引用的文献
1
Gamma globulin complexes in rheumatoid arthritis and certain other conditions.类风湿关节炎及某些其他病症中的γ球蛋白复合物
J Clin Invest. 1961 Jan;40(1):117-29. doi: 10.1172/JCI104224.
2
3
Benign hypergammaglobulinemic purpura of Waldenström.
Medicine (Baltimore). 1971 Mar;50(2):113-23. doi: 10.1097/00005792-197103000-00003.
4
A case of purpura hyperglobulinaemica of Waldenström studied by skin immunofluorescence.
Br J Dermatol. 1974 Nov;91(5):563-8. doi: 10.1111/j.1365-2133.1974.tb12945.x.
5
Purpura hyperglobulinemia.高球蛋白血症性紫癜
Arch Dermatol. 1966 Nov;94(5):536-41.
6
Gamma globulin complexes in rheumatoid arthritis and hypergammaglobulinemic purpura.类风湿性关节炎和高丙种球蛋白血症性紫癜中的γ球蛋白复合物
J Rheumatol. 1974 Mar;1(1):54-65.
7
Characterization of an IgA rheumatoid factor: finding properties and reactivity with the subclasses of human G globulin.一种IgA类风湿因子的特性：发现其与人类γ球蛋白亚类的特性及反应性。
Immunochemistry. 1972 Mar;9(3):301-15. doi: 10.1016/0019-2791(72)90094-8.
8
Hypergammaglobulinemic purpura. Studies on the unusual anti- -globulins characteristic of the sera of these patients.
Medicine (Baltimore). 1971 Mar;50(2):125-38.
9
Relationship between paraprotein polymerization and clinical features in IgA myeloma.IgA 骨髓瘤中副蛋白聚合与临床特征的关系
Br J Haematol. 1976 May;33(1):117-30. doi: 10.1111/j.1365-2141.1976.tb00978.x.
10
The hyperviscosity syndrome in rheumatoid arthritis due to intermediate complexes formed by self-association of IgG-rheumatoid factors.类风湿关节炎中由IgG类风湿因子自缔合形成的中间复合物所致的高黏滞综合征。
Arthritis Rheum. 1975 Mar-Apr;18(2):97-106. doi: 10.1002/art.1780180201.
Zotero 插件