Shirai T, Arai M, Sakata T, Fukushima S, Ito N
Acta Pathol Jpn. 1984 Mar;34(2):417-24. doi: 10.1111/j.1440-1827.1984.tb07570.x.
Two cases of carcinoma arising from the urinary bladder diverticulum were found at autopsy. Both patients had hematuria as a chief complaint and were found to have a tumor mass in the bladder on cystoscopic examination. However, owing to various difficulties the tumors could not be diagnosed before death. Autopsy revealed that the tumors in both cases had arisen within diverticula and had grown into the orifice of the diverticula giving the appearance of ordinary bladder tumors. Histological examination showed that in Case 1, two carcinomas, a keratinizing squamous cell carcinoma and a transitional cell carcinoma, had developed separately in a diverticulum. This may be the first case report of two cancers in a bladder diverticulum. There were no metastases in this case. Case 2 had an undifferentiated carcinoma with metastases to many organs including the lung, liver, and lymph nodes.
尸检发现两例膀胱憩室癌。两名患者均以血尿为主诉，膀胱镜检查发现膀胱有肿瘤肿块。然而，由于各种困难，肿瘤在死亡前未能确诊。尸检显示，两例肿瘤均起源于憩室内，并长入憩室开口，外观类似普通膀胱肿瘤。组织学检查显示，病例1中，一个憩室内分别发生了两种癌，即角化鳞状细胞癌和移行细胞癌。这可能是膀胱憩室内发生两种癌症的首例病例报告。该病例无转移。病例2为未分化癌，已转移至包括肺、肝和淋巴结在内的多个器官。
