Bates C E, Van Dam C H
J Epidemiol Community Health. 1984 Jun;38(2):127-30. doi: 10.1136/jech.38.2.127.
Schizophrenia rates were obtained from a British Columbia coastal Indian group numbering 14 000. One subgroup numbering 12 200 showed an incidence of 10 cases per 100 000 population a year. An atypical subgroup of 1800 showed an incidence of 49 cases per 100 000 a year. These rates appear to be relevant to a hypothesis that suggests that schizophrenia may be caused by abnormal fatty acid metabolism. A study is reviewed which implies the existence of a delta-5 or delta-6 desaturase enzyme mutation or both, in the Indian population under study.
精神分裂症发病率数据来自不列颠哥伦比亚省沿海一个有14000人的印第安人群体。其中一个12200人的亚组显示每年每10万人口中有10例发病。一个1800人的非典型亚组显示每年每10万人口中有49例发病。这些发病率似乎与一个假说相关，该假说认为精神分裂症可能由异常脂肪酸代谢引起。一项研究被综述，该研究暗示在被研究的印第安人群体中存在δ-5或δ-6去饱和酶基因突变，或两者皆有。
