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[非霍奇金淋巴瘤的免疫学]

[Immunology of non-Hodgkin lymphomas].

作者信息

Ricci C, Cascio G, Bellone G, Borio T, Novarini M, Riposio A, Bozzone D

出版信息

Minerva Med. 1983 May 12;74(20):1145-56.

PMID:6431332
Abstract

Cytological and kinetic immunological homogeneity is typical of such lymphomas. Their cytogenesis is broadly connected to the development and differentiation of lymphocytes. It is mainly a question of proliferating B lymphocytes of which the monoclonal membrane receptors are tumoral markers. The final stage of B lymphocyte differentiation is the lymphoplasmacellular proliferation involving monoclonal Ig secretion and consequently the rarefaction and finally disappearance of surface receptors.

摘要

这类淋巴瘤具有典型的细胞学和动力学免疫同质性。它们的细胞发生与淋巴细胞的发育和分化广泛相关。主要涉及增殖的B淋巴细胞,其单克隆膜受体是肿瘤标志物。B淋巴细胞分化的最后阶段是淋巴浆细胞增殖,涉及单克隆Ig分泌,从而导致表面受体减少并最终消失。

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