Rome E S, Stork E K, Carlo W A, Martin R J
Pediatrics. 1984 Aug;74(2):217-20.
Despite the well-documented correlation between transcutaneous and arterial PO2 and PCO2 in sick neonates, the effect of maturation on this relationship has not been well characterized. Eight premature infants with bronchopulmonary dysplasia (BPD) and indwelling arterial lines beyond the immediate neonatal period were studied. Transcutaneous PO2 always underestimated PaO2 beyond 10 weeks of postnatal life, such that transcutaneous PO2 - PaO2 was -16 +/- 5 torr (P less than .001). Corrected transcutaneous PCO2 simultaneously overestimated PaCO2 by 9 +/- 3 torr (P less than .001), although this occurred over a wider range of postnatal ages. Transcutaneous PO2 monitoring may be a useful tool for estimating PaO2 in this population, provided an appropriate correction is made beyond 10 weeks of age. It is suggested that caution be exercised when using transcutaneous PCO2 measurements to estimate absolute arterial values in older infants with bronchopulmonary dysplasia.
尽管患病新生儿经皮和动脉血氧分压（PO2）及二氧化碳分压（PCO2）之间的相关性已有充分记录，但成熟度对这种关系的影响尚未得到很好的描述。对8名患有支气管肺发育不良（BPD）且在新生儿期后留置动脉导管的早产儿进行了研究。出生后10周后，经皮PO2始终低于动脉血氧分压（PaO2），经皮PO2 - PaO2为-16±5托（P<0.001）。校正后的经皮PCO2同时高于PaCO2 9±3托（P<0.001），尽管这种情况发生在更广泛的出生后年龄范围内。经皮PO2监测可能是估计该人群PaO2的有用工具，前提是在10周龄后进行适当校正。建议在使用经皮PCO2测量来估计患有支气管肺发育不良的大龄婴儿的绝对动脉值时要谨慎。
