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金在暴露于硫代苹果酸金钠的大鼠垂体前叶中的定位。

Localization of gold in the anterior pituitary gland of rats exposed to sodium aurothiomalate.

作者信息

Møller-Madsen B, Thorlacius-Ussing O

出版信息

Exp Mol Pathol. 1984 Aug;41(1):74-80. doi: 10.1016/0014-4800(84)90009-1.

DOI:10.1016/0014-4800(84)90009-1
PMID:6432575
Abstract

The ultrastructural localization of gold in the anterior pituitary of rats injected intraperitoneally with sodium aurothiomalate has been demonstrated using a histochemical technique that visualizes minute traces of gold. Gold was located intracellularly within lysosome-like bodies of marginal layer cells, follicular cells, and thyrotrophs. Gold was not seen within secretion granules. The possible mechanism by which gold is taken up into the cells is discussed.

摘要

利用一种能使微量金可视化的组织化学技术,已证实腹腔注射硫代苹果酸金钠的大鼠垂体前叶中金的超微结构定位。金位于边缘层细胞、滤泡细胞和促甲状腺激素细胞的溶酶体样小体内的细胞内。在分泌颗粒中未见到金。文中讨论了金被细胞摄取的可能机制。

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