Koldovský O
J Am Coll Nutr. 1984;3(2):131-8. doi: 10.1080/07315724.1984.10720044.
Two aspects of the physiology of the developing gastrointestinal tract are discussed. The first one deals with functional peculiarities of the developing gastrointestinal tract. Examples are shown that less active function in the suckling (eg, low pepsin digestion in the newborn stomach) may actually give the suckling an advantage for another process. The existence of pH close to neutrality in the suckling's stomach enables "survival" of the milk and lingual lipases that are then "cooperating" with low pancreatic lipase known to be present in the sucklings. The other aspect discussed deals with the role of various factors involved in postnatal maturation of the gastrointestinal function. Using sucrase activity as an example, the important role and mutual interaction of fetal (genetic?) programming, dietary changes, and hormonal maturation are reviewed.
本文讨论了发育中的胃肠道生理学的两个方面。第一个方面涉及发育中胃肠道的功能特性。文中举例表明，哺乳时功能不太活跃（例如新生儿胃中胃蛋白酶消化能力低）实际上可能使哺乳在另一个过程中具有优势。哺乳时胃中接近中性的pH值能使乳汁和舌脂肪酶“存活”，然后这些酶与已知存在于哺乳婴儿体内的低活性胰腺脂肪酶“协同作用”。讨论的另一个方面涉及参与胃肠道功能产后成熟的各种因素的作用。以蔗糖酶活性为例，综述了胎儿（遗传？）编程、饮食变化和激素成熟的重要作用及相互作用。
