Field M, Musch M W, Miller R L, Goetzl E J
J Allergy Clin Immunol. 1984 Sep;74(3 Pt 2):382-5. doi: 10.1016/0091-6749(84)90135-0.
Intestine (both small and large) secretes chloride in response to prostaglandins and agents, such as bradykinin, that increase prostaglandin synthesis. The colon, but not the small intestine, can also be stimulated to secrete chloride by certain lipoxygenase products, such as 5-hydroperoxy-eicosatetraenoic acid and 5-hydroxy-eicosatetraenoic acid, but not by leukotrienes. Intestine generates these compounds and leukotriene B4 (but not C, D, and E) and their synthesis is increased by melittin, calcium ionophore A23187, and bradykinin.
肠道（包括小肠和大肠）会响应前列腺素以及诸如缓激肽等能增加前列腺素合成的物质而分泌氯离子。结肠而非小肠，也可被某些脂氧合酶产物（如5-氢过氧化二十碳四烯酸和5-羟基二十碳四烯酸）刺激分泌氯离子，但白三烯无此作用。肠道会生成这些化合物以及白三烯B4（而非白三烯C、D和E），并且蜂毒肽、钙离子载体A23187和缓激肽会增加它们的合成。
