Boucekkine C, Benmiloud M, Himeur B, Chouiter A, Bachammar M
J Endocrinol Invest. 1984 Jun;7(3):225-30. doi: 10.1007/BF03348428.
H-Y activity, endocrine function and gonadal histology were studied in a phenotypic female presenting with features of sporadic 46,XY pure gonadal dysgenesis. H-Y activity was absent, hormonal data revealed a primary ovarian failure with a blunted response of FSH to LHRH; there was no testicular tissue nor microscopic evidence of gonadal tumor in the gonads. The current view on the role of H-Y antigen in the differentiation of the gonads and in the occurrence of gonocytoma is discussed.
对一名表现出散发性46,XY单纯性腺发育不全特征的表型女性进行了H-Y活性、内分泌功能和性腺组织学研究。未检测到H-Y活性，激素数据显示原发性卵巢功能衰竭，FSH对LHRH反应迟钝；性腺中未发现睾丸组织，也没有性腺肿瘤的微观证据。本文讨论了目前关于H-Y抗原在性腺分化和性腺细胞瘤发生中的作用的观点。
