Zieglauer H, Höpfl-Kreiner I
Padiatr Padol. 1978;13(2):165-73.
Giardia lamblia has a cosmopolitan distribution. The organism exists in two stages--the trophozoite and the cystic stage. Infected children may have acute or chronic diarrhea, crampy abdominal pain, anorexia, malasorption and poor weight gain and may be misdiagnosed as celiac disease. Infection may be selflimited or chronic even over years. Diagnosis is usually made by finding the characteristic cyst in stool specimens or by duodenal aspiration. Histological sections and impression smears (AMENT) of intestinal mucosa biopsies have been proved to be the most reliable method for detecting giardiasis. Evaluation of impression smears for parasites is easier and quicker than examining serial sections of biopsies. Out of 175 selected patients with intestinal complaints which were undergone small intestinal biopsy 11 were infected with giardia lamblia (6.2%). All infected children were symptomatic, malabsorption could be demonstrated in 5/8, lactase levels were reduced in most children. Examination of duodenal aspirates, stool specimens and histological sections (routine histology) alone would not have been diagnostic in every case. Evaluation of impression smears proved to be a reliable method in detecting giardia lamblia infection and is recommended whenever an intestinal biopsy is performed.
蓝氏贾第鞭毛虫分布于世界各地。该生物体存在两个阶段——滋养体阶段和包囊阶段。受感染的儿童可能出现急性或慢性腹泻、痉挛性腹痛、厌食、吸收不良和体重增加缓慢，可能被误诊为乳糜泻。感染可能是自限性的，也可能持续数年呈慢性。诊断通常通过在粪便标本中发现特征性包囊或十二指肠抽吸来进行。肠道黏膜活检的组织学切片和印片（阿门特法）已被证明是检测贾第虫病最可靠的方法。对寄生虫印片的评估比对活检连续切片的检查更容易、更快捷。在175例因肠道不适接受小肠活检的选定患者中，11例感染了蓝氏贾第鞭毛虫（6.2%）。所有受感染的儿童都有症状，8例中有5例可证明有吸收不良，大多数儿童乳糖酶水平降低。仅检查十二指肠抽吸物、粪便标本和组织学切片（常规组织学）并非在每种情况下都能确诊。印片评估被证明是检测蓝氏贾第鞭毛虫感染的可靠方法，建议在进行肠道活检时采用。
