Sugiyama T
Yale J Biol Med. 1983 Sep-Dec;56(5-6):691-3.
Washed cells of Mycoplasma pneumoniae mixed with complete Freund's adjuvant were capable of producing lethal anaphylactic shock in mice when injected repeatedly into the foot pad. The causative agent is associated with horse serum contained in the culture medium but cannot be removed from mycoplasmal cells by repeated washing with phosphate buffered saline. Mycoplasmas grown in medium containing rabbit serum had a similar effect. No lethal anaphylaxis occurs when M. pneumoniae is injected without adjuvant.
将肺炎支原体的洗涤细胞与完全弗氏佐剂混合后,反复注射到小鼠脚垫中能够引发致死性过敏休克。病原体与培养基中所含的马血清有关,但用磷酸盐缓冲盐水反复洗涤支原体细胞无法将其去除。在含有兔血清的培养基中生长的支原体也有类似作用。当无佐剂注射肺炎支原体时,不会发生致死性过敏反应。