Franchi F, De Rosa F, Seminara P, Calvieri S, Carfagna G F, Bosman C
Acta Haematol. 1984;72(1):14-20. doi: 10.1159/000206349.
The 4th case of plasma cell neoplasm associated with a hypereosinophilic syndrome is described and compared with the previous reports. Hypereosinophilia in the present patient displayed some borderline traits with eosinophilic leukemia. Myeloproliferative disorders of the eosinophilic line often present as a precancerous state, but sometimes they seem to acquire malignant independence. In our patient the occurrence of a plasmocytoma with a dramatic course leads to suspect an underlying complex genetic aberration.
本文描述了第4例与嗜酸性粒细胞增多综合征相关的浆细胞肿瘤，并与之前的报告进行了比较。该患者的嗜酸性粒细胞增多表现出一些与嗜酸性粒细胞白血病的临界特征。嗜酸性粒细胞系的骨髓增殖性疾病常表现为癌前状态，但有时似乎会获得恶性独立性。在我们的患者中，浆细胞瘤的发生过程剧烈，这使得人们怀疑其存在潜在的复杂基因畸变。
