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人体中生长抑素的释放及血浆分子生长抑素成分

Somatostatin release and plasma molecular somatostatin components in man.

作者信息

Burhol P G, Lygren I, Jenssen T G, Florholmen J, Jorde R

出版信息

Acta Physiol Scand. 1984 Jul;121(3):223-8. doi: 10.1111/j.1748-1716.1984.tb07450.x.

DOI:10.1111/j.1748-1716.1984.tb07450.x
PMID:6433648
Abstract

The present paper describes a sensitive, precise and specific radioimmunoassay method for measurements of plasma somatostatin; significant rises in plasma somatostatin following a test meal, intraduodenal infusion of fat and HCl, and intravenous injection of insulin; and separation of immunoreactive plasma somatostatin into two components probably representing bound and free molecular forms of somatostatin both in fasting and postprandial human plasmas.

摘要

本文描述了一种用于测量血浆生长抑素的灵敏、精确且特异的放射免疫分析方法;进食试验餐、十二指肠内输注脂肪和盐酸以及静脉注射胰岛素后血浆生长抑素显著升高;以及在空腹和餐后人体血浆中,将免疫反应性血浆生长抑素分离为可能代表生长抑素结合和游离分子形式的两个组分。

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1
Somatostatin release and plasma molecular somatostatin components in man.人体中生长抑素的释放及血浆分子生长抑素成分
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Iodination with Iodo-gen and radioimmunoassay of cholecystokinin (CCK) in acidified plasma, CCK release, and molecular CCK components in man.使用碘酰氯进行碘化以及对人酸化血浆中的胆囊收缩素(CCK)、CCK释放和分子CCK成分进行放射免疫测定。
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Effects of test meal, intragastric nutrients, and intraduodenal bile on plasma concentrations of immunoreactive somatostatin and vasoactive intestinal peptide in dogs.试验餐、胃内营养物质及十二指肠内胆汁对犬血浆免疫反应性生长抑素和血管活性肠肽浓度的影响。
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Plasma cholecystokinin responses after ingestion of liquid meal and intraduodenal infusion of fat, amino acids, or hydrochloric acid in man: analysis with region specific radioimmunoassay.人体摄入流食以及十二指肠内输注脂肪、氨基酸或盐酸后血浆胆囊收缩素反应:采用区域特异性放射免疫分析法进行分析
Am J Gastroenterol. 1983 Nov;78(11):703-7.

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Stimulation of insulin and somatostatin release by two meglitinide analogs.
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Somatostatin.生长抑素
Br Med J (Clin Res Ed). 1987 Aug 1;295(6593):288-90. doi: 10.1136/bmj.295.6593.288.
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Gastrointestinal peptides in serum and synovial fluid from patients with inflammatory joint disease.炎症性关节病患者血清和滑液中的胃肠肽。
Ann Rheum Dis. 1986 Aug;45(8):637-40. doi: 10.1136/ard.45.8.637.
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The neuropeptide head activator loses its biological acitivity by dimerization.神经肽头部激活剂通过二聚化失去其生物活性。
EMBO J. 1986 Aug;5(8):1825-9. doi: 10.1002/j.1460-2075.1986.tb04433.x.