Scoggin C H
Clin Ther. 1984;6(5):603-12.
Terbutaline sulfate, a relatively selective beta2 agonist, is indicated for the treatment of bronchospasm associated with chronic obstructive pulmonary disease. Studies have shown that when administered via an aerosol, terbutaline has a rapid onset, a prolonged duration of action, and a low incidence of systemic side effects. Because the drug is delivered directly to the bronchi, one can administer low doses of aerosolized terbutaline and achieve a bronchodilatory effect comparable to that achieved with higher doses of the oral form.
硫酸特布他林是一种相对选择性的β2受体激动剂,适用于治疗与慢性阻塞性肺疾病相关的支气管痉挛。研究表明,通过气雾剂给药时,特布他林起效迅速、作用持续时间长且全身副作用发生率低。由于药物直接送达支气管,因此可以给予低剂量的雾化特布他林,其支气管扩张效果与高剂量口服剂型相当。