Anderson K V, Nüsslein-Volhard C
Nature. 1984;311(5983):223-7. doi: 10.1038/311223a0.
Maternal-effect mutations in 10 loci in Drosophila produce totally 'dorsalized' embryos. Injection of RNA isolated from wild-type embryos into mutants at six loci partially restores dorsal-ventral polarity. For the mutant snake, injection of poly(A)+ RNA restores a complete dorsal-ventral pattern.
果蝇中10个基因座的母体效应突变会产生完全“背化”的胚胎。将从野生型胚胎中分离的RNA注射到6个基因座的突变体中,可部分恢复背腹极性。对于突变体snake,注射poly(A)+ RNA可恢复完整的背腹模式。