Seemann W R, Mathias K, Urbanyi B, Billmann P
Rofo. 1984 Sep;141(3):333-7. doi: 10.1055/s-2008-1053142.
Experiments in 12 dogs have shown that intra-arterial injection of hyperosmolar contrast into the superior mesenteric artery normally produces a 52% increase in blood flow lasting more than two minutes. Following digitalis-induced mesenteric ischaemia, vaso-dilatation is equally marked, but lasts two and a half times as long. In view of the prolonged vaso-dilator effect of hyperosmolar contrast, arterial spasm could be missed during angiography.
在12只狗身上进行的实验表明，将高渗造影剂经动脉注入肠系膜上动脉，通常会使血流量增加52%，并持续超过两分钟。在洋地黄引起肠系膜缺血后，血管扩张同样明显，但持续时间延长至两倍半。鉴于高渗造影剂具有延长的血管扩张作用，在血管造影过程中可能会漏诊动脉痉挛。
