Prozorovskiĭ S V, Ignatovich V F, Alekseeva N V, Kniazeva E N, Barkhatova O I
Zh Mikrobiol Epidemiol Immunobiol. 1984 Aug(8):92-5.
An indirect modification of the radioimmunoassay (RIA) was shown to be highly sensitive in the determination of the minimal amounts of R. prowazekii and their antigens in the organs and tissues of infected animals. RIA proved to be effective in the determination of the antigens in the blood in cases of R. prowazekii persistence in infected animals. The data obtained in these investigations point to good prospects for using RIA in the study of persistence of microorganisms and their antigens.
已证明，放射免疫测定法（RIA）的一种间接改良法在测定感染动物器官和组织中普氏立克次体及其抗原的最低含量时具有高度敏感性。在感染动物体内存在普氏立克次体的情况下，RIA被证明在测定血液中的抗原方面是有效的。这些研究中获得的数据表明，RIA在研究微生物及其抗原的持续性方面具有良好的前景。
