Machado C R, Moraes-Santos T, Machado A B
Am J Trop Med Hyg. 1984 Sep;33(5):835-8. doi: 10.4269/ajtmh.1984.33.835.
Rats inoculated with Trypanosoma cruzi were divided into two groups maintained, respectively, on a low and a rich protein diet. Ninety-eight days after inoculation the cardiac levels of noradrenalin in the well-nourished infected rats were not different from those of uninfected controls. In the malnourished group, however, these levels were around 50% of the control values. In addition, the adrenergic nerve terminals were clearly reduced in the auricular appendages of 87.5% of the malnourished infected rats. These results indicate that protein deficiency at least delays the recovery of noradrenalin levels that normally occurs during the chronic phase of experimental Chagas' disease.
接种克氏锥虫的大鼠被分为两组，分别给予低蛋白饮食和高蛋白饮食。接种98天后，营养良好的感染大鼠心脏中的去甲肾上腺素水平与未感染的对照组无差异。然而，在营养不良组中，这些水平约为对照值的50%。此外，87.5%的营养不良感染大鼠的心耳附属物中肾上腺素能神经末梢明显减少。这些结果表明，蛋白质缺乏至少会延迟实验性恰加斯病慢性期正常发生的去甲肾上腺素水平的恢复。
