Machado C R, Machado A B, Chiari C A
Am J Trop Med Hyg. 1978 Jan;27(1 Pt 1):20-4. doi: 10.4269/ajtmh.1978.27.20.
Norepinephrine (NE) was assayed fluorimetrically in the hearts of rats killed at different periods after inoculation with the Y strain of Trypanosoma cruzi. The levels of cardiac NE which, as reported previously, were not measurable 18, 22, and 32 days after inoculation became detectable at day 48. At day 70 these levels were around 50% of the control values and at day 97 normal values were attained in most animals. These results strongly suggest that sympathetic nerve fibers are destroyed in the acute phase of T. cruzi infection and regenerated during the chronic phase.
在用克氏锥虫Y株接种后的不同时期处死大鼠，用荧光法测定其心脏中的去甲肾上腺素（NE）。如先前报道，接种后18天、22天和32天心脏NE水平无法测出，但在第48天可检测到。在第70天，这些水平约为对照值的50%，在第97天，大多数动物达到正常水平。这些结果有力地表明，交感神经纤维在克氏锥虫感染的急性期被破坏，并在慢性期再生。
