Donzeau-Gouge P, Blondeau P, Enriquez O, Benomar M, Nottin R, Chauvaud S, Fabiani J N, Tournay D, d'Allaines C, Deloche A
Arch Mal Coeur Vaiss. 1984 Aug;77(8):856-64.
The authors studied 115 surgical cases of calcific aortic stenosis (AS) with coronary angiography. Between 1970 and 1981, 56 of these patients also had one or more aortocoronary bypass grafts (ACBG) (Group I). The other 59 cases, recruited from 1978 to 1981, comprise the control group who underwent isolated aortic valve replacement either with a normal coronary angiogram (Group II: 50 cases) or with such extensive coronary artery disease that ACBG was impossible (Group III: 9 cases). 93% of patients in Group I had preoperative angina compared to 80% in Group II and 78% in Group III. The incidence of previous myocardial infarction was 19%, 4% and 44% respectively. The number of main coronary arterial lesions per patient was 2 in Group I and 1.8 in Group III. In Group I, aortic valve replacement (AVR) was associated with a single aorto-coronary bypass in 70% of cases, a double bypass in 27% and a triple bypass in 3% of cases. The revascularisation ratio was 1.3 bypass per patient. The number of "complete" revascularisations rose from 56% (1970-1976) to 73% from 1977 to 1981. Overall hospital mortality per group (less than 1 month) was 16%, 4% and 0% respectively. The mortality rate in Group I fell from 31% (1970-1976) to 10% from 1977 to 1981. The perioperative rate of myocardial infarction in each group was 9%, 0% and 11% respectively. This figure fell considerably in Group I from 12.5% (1970-1976) to 7.5% from 1977 to 1981.(ABSTRACT TRUNCATED AT 250 WORDS)
作者对115例钙化性主动脉瓣狭窄(AS)手术病例进行了冠状动脉造影研究。1970年至1981年间,其中56例患者还接受了一次或多次主动脉冠状动脉搭桥术(ACBG)(第一组)。另外59例病例于1978年至1981年招募,构成对照组,他们接受了单纯主动脉瓣置换术,其中冠状动脉造影正常的有50例(第二组),冠状动脉疾病严重以至于无法进行ACBG的有9例(第三组)。第一组93%的患者术前有心绞痛,第二组为80%,第三组为78%。既往心肌梗死的发生率分别为19%、4%和44%。每组患者主要冠状动脉病变的数量,第一组为2个,第三组为1.8个。在第一组中,70%的病例主动脉瓣置换(AVR)与单根主动脉冠状动脉搭桥相关,27%为双搭桥,3%为三搭桥。血管重建率为每位患者1.3根搭桥。“完全”血管重建的比例从1970 - 1976年的56%升至1977年至1981年的73%。每组(不到1个月)的总体医院死亡率分别为16%、4%和0%。第一组的死亡率从1970 - 1976年的31%降至1977年至1981年的10%。每组围手术期心肌梗死发生率分别为9%、0%和11%。这一数字在第一组中从1970 - 1976年的12.5%大幅降至1977年至1981年的7.5%。(摘要截断于250字)