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既往冠状动脉旁路移植术后的主动脉瓣手术。钙化和瓣叶运动的影响。

Aortic valve surgery following previous coronary artery bypass grafting. Impact of calcification and leaflet movement.

作者信息

Eitz T, Kleikamp G, Minami K, Gleichmann U, Körfer R

机构信息

Department of Thoracic and Cardiovascular Surgery, Heart and Diabetes Center of North-Rhine-Westfalia, Bad Oeynhausen, Germany.

出版信息

Int J Cardiol. 1998 Apr 1;64(2):125-30. doi: 10.1016/s0167-5273(98)00018-7.

Abstract

We reviewed the reports of 27 patients who had an aortic valve replacement after previous coronary artery bypass grafting. The aortic valve disease -- mainly aortic stenosis -- showed a rapid rate of progression. In the time interval between coronary artery bypass grafting and aortic valve replacement of 4.6+/-2.2 years the peak-to-peak pressure gradient of the aortic valve rose from 20.2+/-14.3 to 63.0+/-22.7 mmHg. As there is a great interest to identify the patients with a high risk of a rapid progression because of a high mortality of an aortic valve replacement as the second cardiac operation following a coronary artery bypass grafting we also reviewed the cardiac catheterisation films and found a high incidence of calcification and impaired aortic valve motion (81.5% of the patients had already calcified aortic valves and 81.5% had a impaired valve motion) at the time of coronary artery bypass grafting. We concluded that if a patient has to be operated for coronary artery disease an aortic valve replacement should be considered not only according to hemodynamic criteria but also when the aortic valve is calcified or its leaflets' motion is impaired.

摘要

我们回顾了27例曾接受过冠状动脉旁路移植术(CABG)后又进行主动脉瓣置换术患者的报告。主动脉瓣疾病——主要是主动脉瓣狭窄——呈现出快速进展的态势。在CABG与主动脉瓣置换术之间平均4.6±2.2年的时间间隔内,主动脉瓣的峰-峰压差从20.2±14.3 mmHg升至63.0±22.7 mmHg。鉴于因作为冠状动脉旁路移植术后第二次心脏手术的主动脉瓣置换术死亡率较高,人们对识别具有快速进展高风险的患者兴趣浓厚,我们还复查了心导管造影影片,发现在冠状动脉旁路移植术时钙化和主动脉瓣活动受损的发生率很高(81.5%的患者已有主动脉瓣钙化,81.5%的患者瓣膜活动受损)。我们得出结论,若患者必须接受冠状动脉疾病手术,不仅应根据血流动力学标准考虑进行主动脉瓣置换术,而且当主动脉瓣钙化或其瓣叶活动受损时也应考虑。

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