Page E, Machecourt J, Dechelette E, Wolf J E, Bourlard P, Denis B
Arch Mal Coeur Vaiss. 1984 Sep;77(9):1040-5.
Thirteen patients with chronic congestive cardiac failure and refractory oedema were treated by haemodialysis. All patients had severe cardiac failure (Class IV NYHA) due to primary myocardial disease (5 cases), ischaemic heart disease (4 cases) or valvular heart disease (4 cases). Haemodialysis was performed via a Shaldon Y-shaped catheter in the internal jugular vein, with input and output through the same catheter using an alternating clamp. Filtration was carried out through a highly permeable membrane by a simple hydrostatic pressure gradient without a dialysis bath. The sessions were monitored haemodynamically by measuring the pulmonary artery pressures. The mean weight loss was 4.9 +/- 0.4 kg obtained after 3 three hour dialysis sessions with 24 hour intervals between each session (mean filtration flow = 12 ml/min). Hypotension was observed in one patient with low initial pulmonary artery pressures; two patients with severe valvular stenosis (1 mitral stenosis; 1 aortic stenosis) failed to lose weight. In the 10 remaining cases, there was a clearcut symptomatic improvement (5 patients Class III; 5 patients Class II NYHA) with total regression of oedema. There was a significant fall in pulmonary artery (mean PAP 40.5 +/- 6.5 mmHg to 34.6 +/- 6.5 mmHg; p less than 0.001) and pulmonary capillary pressure (27.6 +/- 6.9 mmHg to 22.5 +/- 5.8 mmHg; p less than 0.05) in these 10 cases. Cardiac output did not change significantly (cardiac index 2.2 +/- 0.5 l/m2/min compared to 2.3 +/- 0.4 l/m2/min after dialysis).(ABSTRACT TRUNCATED AT 250 WORDS)
13例慢性充血性心力衰竭伴难治性水肿患者接受了血液透析治疗。所有患者均因原发性心肌病(5例)、缺血性心脏病(4例)或瓣膜性心脏病(4例)而患有严重心力衰竭(纽约心脏病协会IV级)。通过颈内静脉的Shaldon Y形导管进行血液透析,使用交替夹通过同一导管进行进出液。通过简单的静水压梯度通过高通透性膜进行过滤,无需透析液浴。通过测量肺动脉压对透析过程进行血流动力学监测。在每两次透析间隔24小时的情况下,经过3次3小时的透析后,平均体重减轻4.9±0.4kg(平均滤过流量=12ml/分钟)。1例初始肺动脉压较低的患者出现低血压;2例严重瓣膜狭窄患者(1例二尖瓣狭窄;1例主动脉狭窄)体重未减轻。在其余10例患者中,症状有明显改善(5例纽约心脏病协会III级;5例II级),水肿完全消退。这10例患者的肺动脉压(平均肺动脉压从40.5±6.5mmHg降至34.6±6.5mmHg;p<0.001)和肺毛细血管压(从27.6±6.9mmHg降至22.5±5.8mmHg;p<0.05)显著下降。心输出量无显著变化(心脏指数透析前为2.2±0.5l/m²/分钟,透析后为2.3±0.4l/m²/分钟)。(摘要截断于250字)