Sly M R, van der Walt W H, du Bruyn D B, Pettifor J M, Marie P J
Calcif Tissue Int. 1984 Jul;36(4):370-9. doi: 10.1007/BF02405348.
Three groups of young baboons were fed for 16 months on one of three diets. The first group was given a well-tried semisynthetic formula, the second group the same diet save that vitamin D had been omitted, and the third group was given the vitamin D-free diet in which maize replaced the dextrin normally used. Although both groups fed the vitamin D-free diets developed rickets and osteomalacia, the group receiving maize did so far more rapidly and to a much greater degree of severity, as evidenced by clinical, radiological, biochemical, and histological signs. The mechanism by which maize acts remains unclear, but this report serves to emphasize the extremely detrimental effects that might be expected in populations who are deficient in vitamin D and who have predominantly cereal diets.
将三组幼年狒狒分别用三种饮食之一喂养16个月。第一组给予一种经过充分试验的半合成配方饮食，第二组给予相同的饮食，但省去了维生素D，第三组给予不含维生素D的饮食，其中用玉米代替了通常使用的糊精。尽管两组喂食不含维生素D饮食的狒狒都出现了佝偻病和骨软化症，但摄入玉米的那组发病速度更快，病情严重程度也高得多，这从临床、放射学、生物化学和组织学迹象中得到了证实。玉米起作用的机制尚不清楚，但本报告旨在强调，对于缺乏维生素D且主要以谷类食物为饮食的人群，可能会产生极其有害的影响。
