Lescaudron L, Beracochea D, Verna A, Jaffard R
Neurosci Lett. 1984 Sep 7;50(1-3):151-5. doi: 10.1016/0304-3940(84)90478-6.
Quantitative analysis, using histological sections, showed that chronic ethanol consumption in the mouse produced neuronal loss in the medial mammillary bodies. This cellular loss was not uniform and was more marked in posterior (-30.1%) than in anterior (-8.8%) parts. Moreover, a reduction of the nucleus diameter of the remaining neurons was found. These results are in agreement with patterns of neuroanatomical damage observed in human alcoholics.
使用组织学切片进行的定量分析表明，小鼠长期摄入乙醇会导致乳头体中部神经元丧失。这种细胞丧失并不均匀，后部（-30.1%）比前部（-8.8%）更明显。此外，还发现剩余神经元的细胞核直径减小。这些结果与在人类酗酒者中观察到的神经解剖学损伤模式一致。
