Pavlinov S A, Isachenkov V A
Probl Endokrinol (Mosk). 1978 Mar-Apr;24(2):102-6.
The absence of hydroxinol-o-methyltrapherase, the terminal enzyme in the chain of melatonin biosynthesis in the gastrointestinal tract of rats was revealed by means of radioisotopic biochemical methods. A high endogenous methylation in the mucosa of the small intestine of rats with the participation of S-adenozylmethionine, differing from melatonin synthesis in the epiphysis, was revealed during this study.
通过放射性同位素生化方法发现，大鼠胃肠道褪黑素生物合成链中的末端酶——羟氧萘-o-甲基转移酶缺失。在本研究中还发现，在S-腺苷甲硫氨酸参与下，大鼠小肠黏膜存在高内源性甲基化，这与松果体中的褪黑素合成不同。
