Kako N, Kimura Y, Kawaguchi T, Soejima S, Koie H
Nihon Geka Gakkai Zasshi. 1984 Sep;85(9):979-84.
Effects of intravenous hyperalimentation (IVH) were studied in 38 patients with anastomotic leakage following gastrointestinal surgery. Spontaneous closure of the leakage were found in 23 patients (60%), and surgical closure were needed in 9 patients (24%). The duration required for spontaneous closure was 5 weeks on the average; and closure occurred readily in cases of tubular fistula. Death occurred in 6 patients (16%); among these, 5 were MOF cases. The following three points are emphasized concerning measures to increase IVH efficacy in serious cases such as MOF. GFX-solution is efficacious for reduced glucose tolerance. Administration of canrenoate potassium(Soldactone), linoleic acid and BCAA enriched amino-acid mixture is effective for accelerated albumin synthesis. Concomitant treatment by IVH and ED(elemental diet) is efficacious in cases of high caloric administration.
对38例胃肠手术后发生吻合口漏的患者进行了静脉高营养(IVH)效果的研究。23例患者(60%)漏口自然闭合,9例患者(24%)需要手术闭合。自然闭合所需时间平均为5周;管状瘘病例中漏口很容易闭合。6例患者(16%)死亡;其中5例为多器官功能衰竭(MOF)病例。关于在MOF等严重病例中提高IVH疗效的措施,强调以下三点。GFX溶液对糖耐量降低有效。给予螺内酯(安体舒通)、亚油酸和富含支链氨基酸的氨基酸混合物对加速白蛋白合成有效。在高热量给药的情况下,IVH与要素饮食(ED)联合治疗有效。