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通过甲状腺与环状软骨融合矫正喉上神经麻痹的实验研究

Experimental studies for correction of superior laryngeal paralysis by fusion of the thyroid to cricoid cartilages.

作者信息

Thompson J W, Ward P H, Schwartz I R

出版信息

Otolaryngol Head Neck Surg. 1984 Oct;92(5):498-508. doi: 10.1177/019459988409200502.

DOI:10.1177/019459988409200502
PMID:6438580
Abstract

Contraction of the cricothyroideus muscles (CTMs), innervated by the superior laryngeal nerves (SLNs), modulates the voice by tilting the thyroid cartilage anteriorly onto the top of the cricoid and tensing the vocal cords. Either unilateral or bilateral paralysis of the SLNs is disabling for individuals with above-average voice demands. Some patients never compensate for this paralysis; there is no surgical procedure recognized to correct it. This study tested the hypothesis that surgical fusion of the thyroid and cricoid cartilages anteriorly can correct the problems of SLN injury by duplicating the mechanical tilt of the thyroid onto the cricoid cartilage normally produced by the CTMs. The SLNs were cut in 12 dogs. In six the cricoid and thyroid cartilages were fused anteriorly. Vocal cord and airway function was assessed preoperatively, immediately postoperatively, and 6 to 10 weeks after surgery. Following surgery there was no airway compromise and there appeared to be a more satisfactory compensation for the SLN paralysis in the fused larynges as compared with the unfused controls as determined by cinelaryngoscopic analysis.

摘要

环甲肌(CTM)由喉上神经(SLN)支配,通过将甲状软骨向前倾斜至环状软骨顶部并拉紧声带,来调节嗓音。对于嗓音要求高于平均水平的个体而言,单侧或双侧喉上神经麻痹均会导致功能障碍。一些患者永远无法代偿这种麻痹;目前尚无公认的手术方法来纠正它。本研究检验了这样一个假设,即通过在前方将甲状软骨与环状软骨融合,模拟环甲肌通常产生的甲状软骨向环状软骨的机械倾斜,能够纠正喉上神经损伤的问题。在12只犬身上切断喉上神经。其中6只犬在前方将环状软骨与甲状软骨融合。在术前、术后即刻以及术后6至10周评估声带和气道功能。术后气道未受影响,并且与未融合的对照组相比,通过动态喉镜分析确定,融合后的喉部对喉上神经麻痹的代偿似乎更令人满意。

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