Brahme A, Eenmaa J, Lindbäck S, Montelius A, Wootton P
Radiother Oncol. 1983 Aug;1(1):65-76. doi: 10.1016/s0167-8140(83)80008-5.
The dose distributional properties of a p(50) Be neutron beam using a continuously variable multi-leaf collimator are presented and compared with a 6 MV photon beam. The differences in physical dose delivery between these two radiation modalities are generally insignificant for radiation therapy, and stringent comparisons of neutron and photon treatments should therefore be possible. The flexibility in field shaping with the multi-leaf collimator opens new possibilities in the treatment of complex irregular target volumes. The collimator consists of 40 wedge-shaped leaves that are independently moved under computer control with their collimating surfaces always aligned with the effective radiation source to minimize the penumbra. The leaf collimator eliminates the need for handling of heavy insert collimators and beam blocks at the same time that it allows dynamic conformation therapy with neutrons.
介绍了使用连续可变多叶准直器的p(50)铍中子束的剂量分布特性，并与6兆伏光子束进行了比较。这两种辐射方式在物理剂量传递上的差异对于放射治疗来说通常不显著，因此对中子和光子治疗进行严格比较应该是可行的。多叶准直器在射野成形方面的灵活性为复杂不规则靶区的治疗开辟了新的可能性。该准直器由40个楔形叶片组成，这些叶片在计算机控制下独立移动，其准直表面始终与有效辐射源对齐，以尽量减少半影。叶片准直器消除了处理沉重的插入式准直器和射野挡块的需求，同时允许进行中子动态适形治疗。
