Lucht F, Rifle G, Portier H, Chalopin J M, Bonhomme J
Br Med J (Clin Res Ed). 1984 Dec 15;289(6459):1647-8. doi: 10.1136/bmj.289.6459.1647.
A 24 year old man admitted to hospital with borderline lepromatous leprosy was treated with rifampicin, dapsone, and clofazimine. After four months he developed a reversal reaction and the diagnosis was modified to borderline tuberculoid leprosy. The dose of clofazimine was raised and prednisolone added to the regimen without any symptomatic response. His condition improved dramatically after five plasma exchanges on five successive days.
一名24岁的男性因边缘性瘤型麻风入院,接受利福平、氨苯砜和氯法齐明治疗。四个月后,他出现了逆转反应,诊断改为边缘性结核样型麻风。氯法齐明剂量增加,治疗方案中加用泼尼松龙,但无任何症状改善。在连续五天进行五次血浆置换后,他的病情显著改善。