发育中的人类胎儿大脑和肝脏中的醛糖代谢。
Aldose metabolism in developing human fetal brain and liver.
作者信息
Samanta B K, Chandra N C, Ghosh S, Mukherjee K L
出版信息
Experientia. 1984 Dec 15;40(12):1420-2. doi: 10.1007/BF01951922.
PMID:6439573
Abstract
Aldose reductase, sorbitol dehydrogenase, and glucose-6-phosphate dehydrogenase enzyme activities were studied in human foetal brain and liver at different periods of gestation. Aldose reductase activity in liver disappears after 16 weeks of gestation whereas sorbitol dehydrogenase keeps on increasing in liver as well as in brain. In utero, some glucose metabolism may be mediated through an active sorbitol pathway in human fetuses.
摘要
在妊娠不同阶段，对人胎儿的脑和肝脏中的醛糖还原酶、山梨醇脱氢酶以及葡萄糖-6-磷酸脱氢酶的酶活性进行了研究。肝脏中的醛糖还原酶活性在妊娠16周后消失，而山梨醇脱氢酶在肝脏和脑中均持续增加。在子宫内，人类胎儿的一些葡萄糖代谢可能通过活跃的山梨醇途径介导。
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