Adams F, Larson D L, Goepfert H
Otolaryngol Head Neck Surg. 1984 Dec;92(6):618-24. doi: 10.1177/019459988409200605.
Scant attention has been paid to emotional changes as possible symptoms of impaired cerebral functioning in cancer patients. A retrospective study was conducted to determine the variety of organic brain syndromes (OBS) that presented with depressive symptoms in 20 head and neck cancer patients. The impressions of referring surgeons were in error in 16 patients (80%). Twelve (60%) had unsuspected OBS, with treatment resulting in reversal of symptoms in almost half. Of the eight patients with functional disorders, four received a final diagnosis of depression. Head and neck surgeons should be aware that (1) emotional changes in their patients frequently reflect OBS, some potentially reversible, (2) because of the ages of the patients, senile dementia may be a more common occurrence in head and neck cancer than suspected, and (3) because of the difficulties of evaluating changes in higher mental functions, more neuropsychiatric consultations may be warranted for head and neck patients.
癌症患者脑部功能受损可能出现的情绪变化很少受到关注。开展了一项回顾性研究，以确定20例头颈癌患者中出现抑郁症状的各种器质性脑综合征（OBS）。转诊外科医生的判断在16例患者（80%）中出现错误。12例（60%）患有未被怀疑的OBS，几乎一半患者经治疗后症状得到缓解。在8例功能性障碍患者中，4例最终被诊断为抑郁症。头颈外科医生应意识到：（1）患者的情绪变化常常反映OBS，有些可能是可逆的；（2）由于患者年龄因素，老年痴呆症在头颈癌患者中可能比怀疑的更为常见；（3）由于评估高级心理功能变化存在困难，头颈癌患者可能需要更多的神经精神科会诊。
