Burke W H, Vaughters P D
Poult Sci. 1984 Nov;63(11):2278-84. doi: 10.3382/ps.0632278.
Thyrotropin releasing hormone (TRH) was administered directly into the crops of male broiler chickens. Significant increases in plasma growth hormone (GH) levels were attained within 30 min after administration of saline solutions containing from 10 to 200 micrograms of TRH. Growth hormone levels remained elevated for 120 min when TRH solutions were introduced into crops of ad libitum-fed birds but for a shorter period in fasted birds. Repeated introduction of 200 micrograms of TRH at 30-min intervals failed to sustain elevated plasma GH levels. Introduction of 50 or 200 micrograms of TRH into the crop in a corn meal vehicle caused a marked elevation in plasma GH levels within 30 min. Levels remained significantly elevated up to 90 min after the introduction of the higher dose, but by 120 min posttreatment GH levels were not significantly different than controls. Thyrotropin releasing hormone that had been stored in solution for 24 or 48 hr was nearly as effective in releasing GH as was a freshly prepared solution.
将促甲状腺激素释放激素（TRH）直接注入雄性肉鸡的嗉囊中。在注射含10至200微克TRH的盐溶液后30分钟内，血浆生长激素（GH）水平显著升高。当将TRH溶液引入自由采食鸟类的嗉囊中时，生长激素水平在120分钟内保持升高，但在禁食鸟类中保持升高的时间较短。以30分钟的间隔重复注射200微克TRH未能维持血浆GH水平的升高。在玉米粉载体中将50或200微克TRH引入嗉囊，导致血浆GH水平在30分钟内显著升高。引入较高剂量后，水平在90分钟内仍显著升高，但在治疗后120分钟，GH水平与对照组无显著差异。在溶液中储存24或48小时的促甲状腺激素释放激素在释放GH方面几乎与新鲜制备的溶液一样有效。
