[Relations between spermatozoa density of germ cells of the testis and hormone analyses (especially FSH) in patients with oligozoospermia)].

The study concerns 84 patients with oligozoospermia between 0.3-20.0 mill. spermatozoa/ml. 20 patients with an obstructive azoospermia served as a collective control. From all patients a testicular biopsy from each testis was conducted. Semithin sections of the testicular tissue were made and the different germ cells in the seminiferous tubules were counted. Furthermore the values of FSH, LH and testosterone in the plasma of every patient were determined. There was a significant correlation between sperm count and FSH (r = -0.30, P less than 0.01), n = 84) as well as LH (r = -0.24, P less than 0.05, n = 84). Also the correlations between the counted germ cells and FSH were significant (P less than 0.01). The closest correlation existed between the spermatogonia A pale + A dark and FSH (r = -0.59, n = 104). But there was no biological significance, since the coefficient of these correlations are not close enough to -1.0. Therefore it is concluded, that the parameters of FSH and LH are not absolutely reliable for judging the spermatogenesis in patients with oligozoospermia.