Cook P T
Anaesth Intensive Care. 1984 Nov;12(4):296-302. doi: 10.1177/0310057X8401200402.
The influence on foetal outcome of maternal PCO2 at caesarean section under general anaesthesia was assessed in 27 "clinically acceptable ideal patients" as defined by Crawford. A standard anaesthetic technique was employed which utilised left lateral tilt and an F1O2 of 0.5. A highly significant relationship (p less than 0.001) was found between umbilical vein PO2 and maternal end-tidal PCO2 in the range 20-40 mmHg, such that hypocarbia was associated with a lowering of umbilical vein PO2. In spite of this relationship, only three values of PO2 were less than normal (28 mmHg). No relationship was found between clinically measured parameters of foetal outcome and maternal end-tidal PCO2. The relevant literature is reviewed.
在27例由克劳福德定义为“临床可接受的理想患者”中，评估了全身麻醉下剖宫产时母体二氧化碳分压（PCO2）对胎儿结局的影响。采用了标准麻醉技术，包括左侧卧位和0.5的吸入氧分数（F1O2）。发现在20 - 40 mmHg范围内，脐静脉血氧分压（PO2）与母体呼气末PCO2之间存在高度显著的关系（p < 0.001），即低碳酸血症与脐静脉PO2降低相关。尽管存在这种关系，但只有三个PO2值低于正常（28 mmHg）。未发现胎儿结局的临床测量参数与母体呼气末PCO2之间存在关系。对相关文献进行了综述。
