Habermann P G, Hünlich T, Kreuzer E, Trotnow S
Geburtshilfe Frauenheilkd. 1984 Oct;44(10):667-9. doi: 10.1055/s-2008-1036328.
The authors report on the case of a 28-year old married woman who was treated according to their IVF-programme after both Fallopian tubes had been removed Three embryo transfers after follicular aspiration by laparoscopy and IVF did not lead pregnancy. In a fourth attempt in May 1984 ovarian stimulation was effected via hMG (Pergonal); 10,000 IU hCG were administered on day 12 of the menstrual cycle. 35 hours later 7 oocytes were recovered via ultrasonically guided percutaneous follicular aspiration under epidural anaesthesia. 3 four-cell embryos were transferred 48 hours after insemination. 9 weeks after l.m.p. sonography showed two intrauterine gestation sacs, in each an embryo of 20 mm C-R length with heart actions and movements.
作者报告了一名28岁已婚女性的病例，该女性双侧输卵管切除后按照他们的体外受精方案进行治疗。腹腔镜检查和体外受精卵泡抽吸后进行了三次胚胎移植均未成功受孕。1984年5月第四次尝试时，通过人绝经期促性腺激素（普果那）进行卵巢刺激；在月经周期的第12天注射10000国际单位的人绒毛膜促性腺激素。35小时后，在硬膜外麻醉下通过超声引导经皮卵泡抽吸回收了7个卵母细胞。授精48小时后移植了3个四细胞胚胎。末次月经后9周超声检查显示两个宫内妊娠囊，每个妊娠囊内有一个头臀长20毫米、有心跳和胎动的胚胎。
