Reichart P, Löning T, Hausamen J E, Becker J
J Oral Pathol. 1984 Dec;13(6):595-603. doi: 10.1111/j.1600-0714.1984.tb01461.x.
Biopsies were taken at 8 and 12 weeks and at 6 months from oral jejunal mucosal transplants in 5 patients who had undergone extensive surgery for tumors of the floor of the mouth. Microvascular anastomosed jejunal mucosa had been used for the primary reconstruction. Histological findings included flattening of the jejunal relief, atrophy and erosion of the epithelium with reduction of jejunal excretion and marginal overlapping of oral mucosa. Immunohistochemical labelling of the cytoskeleton revealed that jejunal epithelium does not undergo rapid metaplasia in the course of adaptation to oral mucosa. These findings indicate that the jejunal mucosa does not completely change its architecture and does not adapt to the requirements of the oral cavity after a period of 6 months.
对5例因口底肿瘤接受广泛手术的患者，在其口腔空肠黏膜移植术后8周、12周和6个月时进行活检。初次重建时采用了微血管吻合的空肠黏膜。组织学检查结果包括空肠皱襞变平、上皮萎缩和糜烂，空肠分泌减少以及口腔黏膜边缘重叠。细胞骨架的免疫组织化学标记显示，空肠上皮在适应口腔黏膜的过程中不会迅速化生。这些发现表明，空肠黏膜在6个月后并未完全改变其结构，也未适应口腔的需求。
