Sasaki T M, Baker H W, McConnell D B, Vetto R M
Arch Surg. 1982 Apr;117(4):459-62. doi: 10.1001/archsurg.1982.01380280043009.
We used microvascular anastomoses to transpose free pedicle jejunal mucosal patch grafts in seven patients. The procedure has been particularly helpful in rebuilding large intra-oral mucosal defects created by extensive resections for advanced carcinomas. Some of the benefits of this technique have included a one-stage procedure, which requires two to three weeks for healing; abundant donor tissue with characteristics similar to oral mucosa; near-normal facial appearance; and preservation of maximum tongue function. An unexpected benefit has been relief of annoying xerostomia by the jejunal mucous secretion. The most severe complication, which resulted in one death, was the excessive oral jejunal mucous secretion in the early postoperative period. It led to significant aspiration pneumonitis. To prevent this problem, we recommend a routine tracheostomy combined with rigorous pulmonary care whenever a jejunal patch graft is used.
我们对7例患者采用微血管吻合术来移植带蒂游离空肠黏膜补片。该手术在重建因晚期癌广泛切除造成的大型口腔内黏膜缺损方面特别有用。这项技术的一些优点包括：一期手术，愈合需要两到三周；供体组织丰富，其特性与口腔黏膜相似；面部外观接近正常；以及最大程度保留舌功能。一个意外的好处是空肠黏液分泌缓解了令人烦恼的口干症。最严重的并发症是术后早期口腔空肠黏液分泌过多，导致1例死亡，引发了严重的吸入性肺炎。为预防这个问题，我们建议每当使用空肠补片移植时，常规行气管切开术并加强肺部护理。
