Frick G, Frick U, Engelmann C, Preussner S, Konrad H, Nowotny P, Keysser M, Bast G
Folia Haematol Int Mag Klin Morphol Blutforsch. 1976;103(5):701-6.
A reduction of the total leukocytes as well as a significant decrease of heparinocytes and BAI (basophilic age index) can be observed in rheumatoid arthritis in the course of a gold therapy. As some coagulation parameters simultaneously speak in favour of an enhancement of the intravasal coagulation, a partial blocking of the endogenous heparin caused by gold may be supposed. A combined heparin or heparinoid therapy in a low dosage is being recommended for risk patients of the vascular and coagulation system.
在类风湿关节炎的金疗法过程中，可以观察到白细胞总数减少，同时肝素细胞和嗜碱性粒细胞年龄指数（BAI）显著下降。由于一些凝血参数同时表明血管内凝血增强，推测金可能导致内源性肝素部分受阻。对于血管和凝血系统的高危患者，建议采用低剂量的联合肝素或类肝素疗法。
