Frick U, Frick G, Preussner S, Konrad H, Nowotny P, Keysser M, Bast G
Folia Haematol Int Mag Klin Morphol Blutforsch. 1976;103(5):715-8.
In 12 patients with chronic rheumatoid arthritis the immunoglobulins IgG, IgA and IgM were determined according to Mancini and the fibrinolytic split products according to Nilehn before and after a gold treatment of 3 to 6 months. The IgG values were always increased and even after the treatment there was only little regression. The fibrinolytic split products found in 5 cases speak in favour of an enhanced intravasal coagulation, which increased still further after the gold therapy. In spite of clinical improvement the immunological processes and latent actions of coagulation seem to pass almost undiminished.
对12例慢性类风湿性关节炎患者,在进行3至6个月的金制剂治疗前后,根据曼奇尼法测定免疫球蛋白IgG、IgA和IgM,根据尼勒恩法测定纤维蛋白溶解产物。IgG值始终升高,即使在治疗后也仅有轻微下降。在5例患者中发现的纤维蛋白溶解产物表明存在血管内凝血增强,在金制剂治疗后进一步加重。尽管临床症状有所改善,但免疫过程和潜在的凝血作用似乎几乎没有减弱。