Solov'ev V V, Borisenko A P, Gruzdev A K, Maĭorov N I, Sergienko V B
Kardiologiia. 1984 Oct;24(10):49-54.
The effect of the intravenous administration of nitroglycerin on the general course of myocardial infarction as well as on such syndromes as acute left ventricular insufficiency, progressive congestive cardiac failure and the recurring painful syndrome was studied. The assessment of the effect of the drug was carried out in relation to its capacity to limit the extension of myocardial infarction and regulate the blood supply to the organs. The data on the frequency and nature of side-effects following nitroglycerin administration are presented. The conclusion is drawn as to the advisability of the drug employment in patients in the acute period of myocardial infarction when it is indicated as well as on the necessity of predicting adverse hemodynamic response to nitroglycerin with the help of suggested diagnostic tests.
研究了静脉注射硝酸甘油对心肌梗死总体病程以及急性左心室功能不全、进行性充血性心力衰竭和复发性疼痛综合征等症状的影响。根据药物限制心肌梗死扩展和调节器官血液供应的能力对其效果进行了评估。给出了硝酸甘油给药后副作用的频率和性质的数据。得出了在心肌梗死急性期有指征时使用该药物的适宜性结论,以及借助建议的诊断试验预测硝酸甘油不良血流动力学反应的必要性结论。