Gerlach H, Bahn H, Wessel H, Stiller D, Holzhausen H J
Zentralbl Allg Pathol. 1984;129(4):343-56.
Report of a 41-year-old man who died from an intracerebrally localized pleomorphic IgM/kappa immunoblastoma 7 1/4 years after the diagnosis of nodular sclerosis in mediastinal lymph nodes and treatment by surgery, radiation and cytostatics. There was no evidence of residual Hodgkin's disease at autopsy. The cases of malignant non-Hodgkin's lymphomas after treated Hodgkin's disease reported in the literature are tabulated. The relationship of these secondary neoplasms to the primary disease and its treatment is discussed.
一名41岁男性的报告,该患者在纵隔淋巴结结节硬化症诊断并接受手术、放疗和细胞抑制剂治疗7又1/4年后,死于脑内局限性多形性IgM/κ免疫母细胞瘤。尸检时未发现残留霍奇金病的证据。文中列出了文献报道的霍奇金病治疗后发生恶性非霍奇金淋巴瘤的病例。讨论了这些继发性肿瘤与原发性疾病及其治疗的关系。