Shapiro M S, Weiss E, Kott E, Taragan R, Shenkman L
J Endocrinol Invest. 1984 Dec;7(6):579-83. doi: 10.1007/BF03349489.
Hypothalamic pituitary function was studied in 13 patients with myasthenia gravis. Gonadotropin, TSH, and prolactin dynamics were investigated using conventional provocative stimuli. No consistent abnormality was found in either gonadotropin or prolactin release. Abnormal TSH responses to TRH administration was present in six of the 13 patients in association with normal free thyroxine indices and the absence of antithyroid antibodies. This latter observation is relevant when the association of myasthenia gravis with hyperthyroidism, thyroiditis and hypothyroidism is considered.
对13例重症肌无力患者的下丘脑垂体功能进行了研究。使用传统的激发刺激来研究促性腺激素、促甲状腺激素和催乳素的动态变化。在促性腺激素或催乳素释放方面均未发现一致的异常。13例患者中有6例对促甲状腺激素释放激素（TRH）给药的促甲状腺激素反应异常，同时游离甲状腺素指数正常且无抗甲状腺抗体。当考虑重症肌无力与甲状腺功能亢进、甲状腺炎和甲状腺功能减退的关联时，后一观察结果具有相关性。
