McGregor D D, Chen-Woan M
Clin Invest Med. 1984;7(4):243-52.
Immunospecific T cells cooperate with macrophages in the expression of delayed type hypersensitivity and cellular resistance to Listeria monocytogenes. The mediator cells involved are generated in response to an immunizing Listeria infection. Immunospecific T cells are formed in lymphoid tissue and appear briefly in the blood. Many localize at sites of microbial implantation, but others leave the blood spontaneously and infiltrate tissues throughout the body. Both circulating T cells and those in tissues participate in the expression of delayed type hypersensitivity and cellular resistance. Several lines of evidence suggest that these two phenomena are mediated by heterogeneous but possibly cooperating T cell populations.
免疫特异性T细胞与巨噬细胞协同作用，表达迟发型超敏反应并对单核细胞增生李斯特菌产生细胞抗性。所涉及的介导细胞是在对免疫性李斯特菌感染作出反应时产生的。免疫特异性T细胞在淋巴组织中形成，并短暂出现在血液中。许多T细胞定位于微生物植入部位，但其他T细胞会自发离开血液并浸润全身组织。循环中的T细胞和组织中的T细胞都参与迟发型超敏反应和细胞抗性的表达。几条证据表明，这两种现象是由异质性但可能相互协作的T细胞群体介导的。
