Bastie-Sigeac I, Paterour M J, Jaurand M C, Bignon J
IARC Sci Publ. 1984(53):301-10.
To examine the toxicity of three nickeliferous ores (Noumea Mines, Société le Nickel, in vitro tests were carried out with mammalian cells: haemolysis of human red blood cells (RBC), release of enzymes by rabbit alveolar macrophages (AM) for studying inflammation, and study of rat pleural mesothelial cells (PMC) to determine the effect on cellular growth and genotoxic effects.
为检测三种含镍矿石(新喀里多尼亚矿业公司、镍业公司)的毒性,利用哺乳动物细胞进行了体外试验:检测人红细胞(RBC)的溶血情况、兔肺泡巨噬细胞(AM)释放酶以研究炎症,以及研究大鼠胸膜间皮细胞(PMC)以确定对细胞生长的影响和遗传毒性作用。