Gräni R, Wandeler A, Steck F, Rösli R
Schweiz Med Wochenschr. 1978 Apr 22;108(16):593-7.
A 57-year-old veterinary surgeon developed rabies 174 days after injury during an oral palpation of a rabid cow. He had been vaccinated prophylactically with Duck embryo vaccine several months before exposure but never had his serum antibody level controlled. He died 45 days later. The prodromal and encephalitic stage lasted 5 days each. Intensive supportive medical treatment was given from the beginning of the paralytic stage. The clinical course was complicated by progredient respiratory failure, diabetes insipidus, severe hypotension, and increase of intracranial pressure. The diagnosis of rabies was confirmed by rising antibody titers prior to the patient's death.
一名57岁的兽医在对一头患狂犬病的奶牛进行口腔触诊时受伤,174天后患上狂犬病。暴露前几个月他曾接受鸭胚疫苗预防性接种,但从未检测过血清抗体水平。45天后他死亡。前驱期和脑炎期各持续5天。从麻痹期开始给予强化支持性治疗。临床过程因进行性呼吸衰竭、尿崩症、严重低血压和颅内压升高而复杂化。患者死亡前抗体滴度升高,确诊为狂犬病。